Details for gene set SECOND_MESSENGER_MEDIATED

Table: GSEA Results Summary

Dataset	RNR_GSEA_DESEQ2_FC
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	SECOND_MESSENGER_MEDIATED_SIGNALING
Enrichment Score (ES)	-0.16715729
Normalized Enrichment Score (NES)	-2.4193773
Nominal p-value	0.0
FDR q-value	0.006961221
FWER p-Value	0.091

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	OPRD1	66	2.581	0.0030	No
2	GCGR	93	2.179	0.0081	No
3	GRM5	156	1.783	0.0113	No
4	F2RL3	164	1.710	0.0174	No
5	SSTR4	172	1.642	0.0236	No
6	CCKBR	274	1.281	0.0247	No
7	NMBR	392	1.026	0.0249	No
8	MTNR1A	398	1.015	0.0311	No
9	MTNR1B	414	1.008	0.0369	No
10	GALR1	513	0.878	0.0381	No
11	SSTR3	579	0.791	0.0411	No
12	HTR2B	649	0.728	0.0439	No
13	NPY1R	670	0.710	0.0494	No
14	GPR3	741	0.644	0.0521	No
15	GRM8	778	0.623	0.0567	No
16	ADCYAP1	901	0.569	0.0566	No
17	GALR3	910	0.567	0.0627	No
18	ADRB3	923	0.559	0.0686	No
19	DRD1	924	0.558	0.0752	No
20	CALCR	1066	0.494	0.0741	No
21	PLCE1	1235	0.428	0.0715	No
22	HTR1D	1309	0.401	0.0741	No
23	HTR1E	1492	0.349	0.0708	No
24	HTR7	1654	0.318	0.0686	No
25	GLP1R	1656	0.318	0.0751	No
26	PTHLH	1769	0.298	0.0756	No
27	CCR3	2026	0.259	0.0682	No
28	GHRHR	2145	0.246	0.0684	No
29	CHRM2	2981	0.174	0.0297	No
30	PIKFYVE	3012	0.172	0.0346	No
31	CAP2	3028	0.171	0.0404	No
32	NF1	3060	0.169	0.0452	No
33	HOMER1	3260	0.157	0.0410	No
34	P2RY4	3560	0.142	0.0313	No
35	ADCY7	3647	0.138	0.0332	No
36	HTR4	3825	0.129	0.0302	No
37	GNAS	3869	0.128	0.0344	No
38	PLCH1	4038	0.121	0.0318	No
39	ANG	4182	0.115	0.0306	No
40	P2RY1	4196	0.115	0.0365	No
41	PRKD3	4499	0.105	0.0267	No
42	CNR2	4697	0.098	0.0225	No
43	CCR2	4737	0.096	0.0270	No
44	PRKACB	4816	0.094	0.0293	No
45	HRH2	5735	0.069	-0.0139	No
46	AVPR1A	5904	0.064	-0.0164	No
47	EDNRA	6041	0.061	-0.0173	No
48	WASF2	6204	0.058	-0.0195	No
49	GRK5	6905	0.042	-0.0508	No
50	GNAI3	6993	0.040	-0.0490	No
51	GABBR1	7283	0.034	-0.0581	No
52	RGN	7383	0.031	-0.0569	No
53	ADORA2B	7487	0.029	-0.0560	No
54	P2RY2	7524	0.028	-0.0514	No
55	HTR1B	7869	0.022	-0.0635	No
56	DRD2	7972	0.020	-0.0624	No
57	GNAQ	8139	0.017	-0.0649	No
58	EDNRB	8261	0.014	-0.0649	No
59	PPAP2A	9181	-0.005	-0.1081	No
60	RGS1	9288	-0.007	-0.1073	No
61	PICK1	10017	-0.021	-0.1402	No
62	PTGIR	10040	-0.021	-0.1348	No
63	NDUFS4	10092	-0.022	-0.1310	No
64	C5AR1	10286	-0.026	-0.1350	No
65	GNAI2	10460	-0.029	-0.1378	No
66	BTK	10686	-0.034	-0.1434	No
67	HRH1	10734	-0.035	-0.1394	No
68	GRM2	10857	-0.038	-0.1395	No
69	CCR1	10867	-0.038	-0.1334	No
70	CDH13	10880	-0.038	-0.1276	No
71	VIPR1	10969	-0.041	-0.1258	No
72	MC1R	11228	-0.047	-0.1332	No
73	CAP1	11285	-0.048	-0.1297	No
74	TBL3	11349	-0.050	-0.1266	No
75	GAP43	11679	-0.058	-0.1378	No
76	EGFR	11807	-0.060	-0.1382	No
77	BUD31	12052	-0.066	-0.1449	No
78	ADORA3	12298	-0.072	-0.1516	No
79	AVPR2	12302	-0.072	-0.1452	No
80	XCR1	12415	-0.075	-0.1447	No
81	ADRA1B	12594	-0.080	-0.1478	No
82	LTB4R2	12821	-0.087	-0.1535	No
83	PARD3	13008	-0.092	-0.1571	No
84	SSTR1	13028	-0.093	-0.1515	No
85	ADRB2	13083	-0.094	-0.1479	No
86	CAMKK2	13180	-0.098	-0.1466	No
87	CCKAR	13360	-0.104	-0.1497	No
88	PTGER4	13389	-0.105	-0.1447	No
89	GIPR	13604	-0.112	-0.1498	No
90	NMUR1	13663	-0.114	-0.1464	No
91	P2RY6	13923	-0.125	-0.1538	No
92	CALCRL	13989	-0.128	-0.1508	No
93	GRM3	14032	-0.130	-0.1466	No
94	CRHR2	14080	-0.132	-0.1426	No
95	CORT	14363	-0.147	-0.1513	No
96	LPAR2	14657	-0.161	-0.1606	Yes
97	ACR	14762	-0.168	-0.1597	Yes
98	LPAR3	14884	-0.177	-0.1597	Yes
99	OPRL1	14942	-0.181	-0.1563	Yes
100	SPHK1	15038	-0.188	-0.1549	Yes
101	AGTR1	15193	-0.200	-0.1567	Yes
102	CHRM1	15266	-0.206	-0.1540	Yes
103	PTH1R	15314	-0.210	-0.1500	Yes
104	CHRM5	15320	-0.211	-0.1438	Yes
105	P2RY11	15504	-0.228	-0.1471	Yes
106	LAT2	15524	-0.230	-0.1416	Yes
107	LTB4R	15563	-0.233	-0.1372	Yes
108	GNA15	15687	-0.247	-0.1373	Yes
109	HTR1F	15742	-0.255	-0.1337	Yes
110	LHCGR	15805	-0.264	-0.1305	Yes
111	ADRB1	15883	-0.273	-0.1281	Yes
112	PTAFR	15996	-0.287	-0.1276	Yes
113	PLCB2	16031	-0.291	-0.1229	Yes
114	NUDT4	16236	-0.324	-0.1275	Yes
115	TSHR	16242	-0.326	-0.1212	Yes
116	S1PR4	16446	-0.365	-0.1256	Yes
117	MC5R	16498	-0.377	-0.1219	Yes
118	GALR2	16500	-0.377	-0.1154	Yes
119	MC4R	16517	-0.380	-0.1097	Yes
120	CCL2	16640	-0.407	-0.1098	Yes
121	LAT	16652	-0.411	-0.1038	Yes
122	GLP2R	16676	-0.419	-0.0985	Yes
123	MCHR1	16745	-0.436	-0.0957	Yes
124	OPRM1	16799	-0.453	-0.0920	Yes
125	TRAT1	16811	-0.456	-0.0861	Yes
126	ADRA1D	16824	-0.461	-0.0802	Yes
127	SLA2	16871	-0.471	-0.0761	Yes
128	NMUR2	16900	-0.480	-0.0711	Yes
129	SSTR2	17118	-0.542	-0.0763	Yes
130	AZU1	17141	-0.551	-0.0710	Yes
131	HRH3	17186	-0.572	-0.0668	Yes
132	ADRA2A	17190	-0.575	-0.0605	Yes
133	SSTR5	17301	-0.629	-0.0599	Yes
134	CNR1	17364	-0.661	-0.0567	Yes
135	GABBR2	17458	-0.711	-0.0552	Yes
136	IL8	17463	-0.715	-0.0489	Yes
137	FPR1	17496	-0.733	-0.0441	Yes
138	HTR6	17531	-0.751	-0.0394	Yes
139	NPY2R	17535	-0.755	-0.0330	Yes
140	CALCA	17537	-0.756	-0.0265	Yes
141	EDN2	17572	-0.781	-0.0218	Yes
142	CXCR2	17578	-0.784	-0.0156	Yes
143	GRM4	17584	-0.793	-0.0093	Yes
144	DRD5	17619	-0.823	-0.0046	Yes
145	OPRK1	17632	-0.832	0.0013	Yes
146	CRHR1	17641	-0.840	0.0074	Yes
147	TACR1	17708	-0.891	0.0104	Yes
148	MC3R	17929	-1.072	0.0050	Yes
149	NPY	18089	-1.220	0.0029	Yes
150	GRM7	18130	-1.297	0.0073	Yes
151	AVPR1B	18370	-1.854	0.0009	Yes
152	GHRH	18373	-1.859	0.0073	Yes
153	MC2R	18444	-2.148	0.0101	Yes